Would Michigan investigators be able to prove murder in a case without a body?

After Dee Warner, a Michigan businesswoman and mother, disappeared from her home, her family believed she has been murdered and suspected her husband Dale Warner. But without physical evidence, they knew it would be hard to prove.

source https://www.cbsnews.com/news/dee-warner-missing-would-michigan-investigators-be-able-to-prove-murder-without-a-body/